The rule-of-thumb is that prostates produce about .066 ng/ml of PSA for every cc of prostate (from "A Primer on Prostate Cancer - The Empowered Patient's Guide," p. F4). Unfortunately, though doctors can make a rough estimate of prostate volume from a DRE, it takes an ultrasound exam or biopsy to get an accurate size. John P. Mulhall, MD, discusses the results and implications of a study evaluating the relationship between testosterone and PSA levels in men with prostate cancer. He suggests that these findings indicate that in men with documented prostate cancer, the presence of a pretreatment PSA value below 2 should raise questions about a patient’s It’s anxiety provoking to have to wait for one or more repeat blood tests to find out if PSA is coming back down. Thankfully, a presentation by Monaco, et al. [iii] at the 2022 annual meeting of the American Urological Association offers some real clues—not red herrings—to help tell whether a rising PSA is more likely a bounce than The PSA doubling time can also detect a relapse of cancer after treatment with surgery or radiation. The time it takes for PSA blood levels to double gives your medical team an insight into how aggressive your prostate cancer will be in the future. That can guide your treatment plan, which may include: Observation. Prostatitis is commonly reported on needle biopsies and 65–70% of patients with abnormal PSA levels do not have cancer on prostate needle biopsy. After a 2-year clinical and biochemical follow-up of symptomatic men who had a high PSA level and a normal DRE, and normal repeat PSA level, PBx can be safely avoided . A raised PSA level can be a sign of prostate cancer. But many men with a raised PSA level don’t have prostate cancer. And some men with a normal PSA level do have prostate cancer. You may be more likely to get prostate cancer if: • you are aged 50 or over, or • your father or brother has had it, or • you are Black. PSA and Testosterone Observations. (see references 1-16) Low Testosterone and Increased Risk Prostate Cancer. (1) Lower Testosterone Levels ( not higher levels) are associated with increased risk for aggressive prostate cancer. Higher levels within the normal range are associated with less risk for Prostate CA. The expected result after prostatectomy is an undetectable PSA or level of 0. The surgery itself is a cornerstone of a mans life, but the tests that follow, especially the PSA test, can be very dreaded. The PSA test is a blood analysis that checks for the level of the prostate-specific antigen in the blood cells. amIUOK.

can psa levels go down